Unconstrained bacterial promiscuity: the Tn916-Tn1545 family of conjugative transposons

Trends Microbiol. 1995 Jun;3(6):229-36. doi: 10.1016/s0966-842x(00)88930-1.


Conjugative transposons are highly ubiquitous elements found throughout the bacterial world. Members of the Tn916-Tn1545 family carry the widely disseminated tetracycline-resistance determinant Tet M, as well as additional resistance genes. They have been found naturally in, or been introduced into, over 50 different species and 24 genera of bacteria. Recent investigations have led to insights into the molecular basis of movement of these interesting mobile elements.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Bacteria / genetics*
  • Conjugation, Genetic / genetics*
  • DNA Transposable Elements / genetics*
  • Plasmids / genetics


  • DNA Transposable Elements