Abstract
Great progress has been made in advancing an atomic-level model for F-actin. A growing body of data shows, however, that any picture of F-actin must take into account allosteric interactions within subunits, long-range cooperative effects that occur between subunits, and the fact that several conformations of the filament can exist.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Actin Cytoskeleton / chemistry*
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Actin Cytoskeleton / physiology
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Actins / chemistry*
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Actins / metabolism*
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Adenosine Triphosphatases / metabolism
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Allosteric Regulation
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Calcium / metabolism
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Crystallography, X-Ray
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Deoxyribonucleases / metabolism
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Models, Molecular
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Myosins / metabolism
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Protein Binding
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Protein Conformation
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Tropomyosin / metabolism
Substances
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Actins
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Tropomyosin
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Deoxyribonucleases
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Adenosine Triphosphatases
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Myosins
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Calcium