A novel thermostable polymerase for DNA sequencing

Nature. 1995 Aug 31;376(6543):796-7. doi: 10.1038/376796a0.

Abstract

Using recent findings by Tabor and Richardson, a novel thermostable DNA polymerase that generates sequence data comparable with T7 Sequenase DNA polymerase has been developed for improved base calling and longer reads.

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • DNA-Directed DNA Polymerase / metabolism*
  • Hot Temperature
  • Molecular Sequence Data
  • Recombinant Fusion Proteins / metabolism
  • Sequence Analysis, DNA / methods*

Substances

  • Recombinant Fusion Proteins
  • bacteriophage T7 induced DNA polymerase
  • DNA-Directed DNA Polymerase