Chemotherapy for gliomas

Curr Opin Oncol. 1995 May;7(3):207-13. doi: 10.1097/00001622-199505000-00003.


Despite advances in surgical and radiation therapy techniques, the prognosis of patients with malignant gliomas remains poor. Few agents have been developed specifically for brain tumors, and the nitrosoureas remain the most active antitumor agents available. In this paper we review the chemotherapeutic and chemoradiation protocols currently being used to treat primary and recurrent gliomas in adults.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adult
  • Antineoplastic Agents / therapeutic use*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Brain Neoplasms / drug therapy*
  • Brain Neoplasms / radiotherapy
  • Clinical Trials as Topic
  • Combined Modality Therapy
  • Glioma / drug therapy*
  • Glioma / radiotherapy
  • Humans


  • Antineoplastic Agents