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, 4 (6), 1073-6

Linkage of a Gene for Dominant Non-Syndromic Deafness to Chromosome 19

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Linkage of a Gene for Dominant Non-Syndromic Deafness to Chromosome 19

A H Chen et al. Hum Mol Genet.

Abstract

Inherited hearing impairment can occur either in the presence of other clinical features (syndromic hearing loss, SHL) or in isolation (non-syndromic hearing loss, NSHL). The latter is more common and is highly heterogeneous. To date, six NSHL loci have been mapped. We report the identification of a seventh locus (DFNA4) on chromosome 19q13 and suggest DM kinase as a possible candidate gene.

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