Mesenchymal chondrosarcoma. A cytogenetic, immunohistochemical and ultrastructural study

S M Dobin; L R Donner; V O Speights Jr

doi:10.1016/0165-4608(95)00031-3

Mesenchymal chondrosarcoma. A cytogenetic, immunohistochemical and ultrastructural study

Cancer Genet Cytogenet. 1995 Aug;83(1):56-60. doi: 10.1016/0165-4608(95)00031-3.

Authors

S M Dobin¹, L R Donner, V O Speights Jr

Affiliation

¹ Department of Pathology, Scott & White Clinic, Temple, Texas 76508, USA.

PMID: 7656206
DOI: 10.1016/0165-4608(95)00031-3

Abstract

A case of mesenchymal chondrosarcoma was studied. The tumor was near-tetraploid and the clonal structural chromosomal abnormalities included add(7)(p13), add(22)(q13), markers, and double minutes. The ultrastructural and immunohistochemical findings were consistent with the diagnosis. Strong immunoreactivity for desmin was an unusual, not previously reported, feature of the neoplasm.

Publication types

Case Reports

MeSH terms

Bone Neoplasms / genetics*
Bone Neoplasms / pathology
Bone Neoplasms / ultrastructure
Chondrosarcoma, Mesenchymal / genetics*
Chondrosarcoma, Mesenchymal / pathology
Chondrosarcoma, Mesenchymal / ultrastructure
Chromosomes, Human, Pair 22
Chromosomes, Human, Pair 7
Humans
Immunohistochemistry
Infant
Karyotyping
Male
Ploidies