Identification of a member of mouse semaphorin family

FEBS Lett. 1995 Aug 21;370(3):269-72. doi: 10.1016/0014-5793(95)00850-9.

Abstract

Grasshopper semaphorin I (Sema I) and its related proteins, chick collapsin and mouse Sema III contribute to the axon guidance by their repellent actions [5,9,12]. We have identified a member of semaphorin gene family from the mouse brain and named it M-Sema F. The N-terminal encodes a semaphorin domain that is similar between Sema I-III [6] followed by a single putative immunoglobulin-like domain, a transmembrane domain, and a proline-rich intracellular domain. M-Sema F mRNA is expressed widely in the nervous tissues during development. These suggest that M-Sema F is a transmembrane member of the semaphorin family of the vertebrate which may function in the developing neuronal network.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Blotting, Northern
  • Cloning, Molecular
  • Female
  • Gene Expression
  • Glycoproteins / chemistry*
  • Glycoproteins / genetics*
  • In Situ Hybridization
  • Mice
  • Molecular Sequence Data
  • Nerve Growth Factors / chemistry*
  • Nerve Growth Factors / genetics*
  • Pregnancy
  • Semaphorin-3A

Substances

  • Glycoproteins
  • Nerve Growth Factors
  • Semaphorin-3A

Associated data

  • GENBANK/S79463