Extraocular muscles: basic and clinical aspects of structure and function

Surv Ophthalmol. 1995 May-Jun;39(6):451-84. doi: 10.1016/s0039-6257(05)80055-4.


Although extraocular muscle is perhaps the least understood component of the oculomotor system, these muscles represent the most common site of surgical intervention in the treatment of strabismus and other ocular motility disorders. This review synthesizes information derived from both basic and clinical studies in order to develop a better understanding of how these muscles may respond to surgical or pharmacological interventions and in disease states. In addition, a detailed knowledge of the structural and functional properties of extraocular muscle, that would allow some degree of prediction of the adaptive responses of these muscles, is vital as a basis to guide the development of new treatments for eye movement disorders.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Eye Movements
  • Humans
  • Macaca
  • Ocular Motility Disorders / pathology
  • Ocular Motility Disorders / physiopathology
  • Ocular Motility Disorders / therapy
  • Oculomotor Muscles / anatomy & histology*
  • Oculomotor Muscles / embryology
  • Oculomotor Muscles / physiology*