Ocular manifestations of diabetes mellitus: diabetic cataracts in dogs

Vet Clin North Am Small Anim Pract. 1995 May;25(3):661-76. doi: 10.1016/s0195-5616(95)50061-0.

Abstract

Cataracts form in diabetic dogs because of the disruption of normal lens metabolism. The pathophysiology seems to be a combination of increased lens cell membrane permeability, reduced cell membrane function, damage from accumulating osmotic products (polyols), glycosylation of lens proteins, and oxidative injury. Lens-induced uveitis must be recognized and managed in presurgical preparation of dogs with diabetes cataracts. Phacoemulsification is the current treatment of choice for diabetic cataracts in dogs and can be performed at an earlier time than traditional extracapsular lens extraction. This may allow for greater success rates after surgery.

Publication types

  • Review

MeSH terms

  • Animals
  • Cataract / etiology
  • Cataract / physiopathology
  • Cataract / veterinary*
  • Cataract Extraction / veterinary
  • Diabetes Complications
  • Diabetes Mellitus / physiopathology
  • Diabetes Mellitus / veterinary*
  • Diabetic Retinopathy / etiology
  • Diabetic Retinopathy / physiopathology
  • Diabetic Retinopathy / veterinary
  • Dog Diseases / etiology*
  • Dog Diseases / physiopathology
  • Dogs
  • Postoperative Care / veterinary
  • Postoperative Complications / veterinary