Impact of age, various forms of cataract, and visual acuity on whole-field scotopic sensitivity screening for glaucoma in rural Taiwan

Arch Ophthalmol. 1995 Sep;113(9):1138-43. doi: 10.1001/archopht.1995.01100090064024.


Objective: To evaluate the impact of age, various forms of cataract, and visual acuity on whole-field scotopic sensitivity screening for glaucoma in a rural population.

Design: Clinic-based study with population-based recruitment.

Setting: Jin Shan Township near Taipei, Taiwan.

Subjects: Three hundred forty-six residents (ages, > or = 40 years) of Jin Shan Township.

Interventions: Whole-field scotopic testing, ophthalmoscopy with dilation of the pupils, cataract grading against photographic standards, and screening visual field testing in a random one-third subsample.

Main outcome measures: Whole-field scotopic sensitivity (in decibels) and diagnostic status as a case of glaucoma, glaucoma suspect, or normal.

Results: Participants in Jin Shan Township did not differ significantly in the rate of blindness, low visual acuity, or family history of glaucoma from a random sample of nonrespondents. Scotopic sensitivity testing detected 100% (6/6) of subjects with open-angle glaucoma at a specificity of 80.2%. The mean +/- SE scotopic sensitivity for six subjects with open-angle glaucoma (32.78 +/- 1.51 dB) differed significantly from that of 315 normal individuals (38.51 +/- 0.22 dB), when adjusted for age and visual acuity (P = .05, t test). With linear regression modeling, factors that correlated significantly with scotopic sensitivity were intraocular pressure, screening visual field, best corrected visual acuity, presence of cortical cataract, and increasing age.

Conclusions: Although cataract affects the whole-field scotopic threshold, it appears that scotopic testing may be of value in field-based screening for glaucoma.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Aging / physiology*
  • Cataract / classification
  • Cataract / physiopathology*
  • Dark Adaptation
  • Female
  • Glaucoma, Open-Angle / diagnosis*
  • Glaucoma, Open-Angle / epidemiology
  • Humans
  • Intraocular Pressure
  • Male
  • Middle Aged
  • Rural Population
  • Sensitivity and Specificity
  • Sensory Thresholds
  • Taiwan / epidemiology
  • Visual Acuity / physiology*
  • Visual Fields*