Two-graph receiver operating characteristic (TG-ROC): a Microsoft-EXCEL template for the selection of cut-off values in diagnostic tests

J Immunol Methods. 1995 Sep 11;185(1):145-6. doi: 10.1016/0022-1759(95)00078-o.


TG-ROC, a template for Microsoft-EXCEL, represents a novel, easy-to-handle approach for selecting cut-off values in quantitative diagnostic tests. In addition to graphical representations of test efficiency, Youden index and likelihood ratios as functions of the preselected cut-off value, the software supports the definition of an intermediate range of test results. For this purpose, two cut-off values are established that realise a pre-selected accuracy level (e.g., 90 or 95% sensitivity and specificity) which can be specified by the user.

MeSH terms

  • Serologic Tests / standards*
  • Software*
  • Statistics as Topic