[A multicenter evaluation of efficacy and tolerance in the local treatment with dolgit cream of patients with osteoarthrosis]

V A Nasonova; Iu V Murav'ev; E L Nasonov; V V Lebedeva; E S Tsvetkova; N V Chichasova; V V Badokin; O M Lesniak; A A Demin; E Ia Baranova

[A multicenter evaluation of efficacy and tolerance in the local treatment with dolgit cream of patients with osteoarthrosis]

Ter Arkh. 1995;67(6):48-50.

[Article in Russian]

Authors

V A Nasonova, Iu V Murav'ev, E L Nasonov, V V Lebedeva, E S Tsvetkova, N V Chichasova, V V Badokin, O M Lesniak, A A Demin, E Ia Baranova, et al.

PMID: 7667780

Abstract

A 2-week clinical trial of cream dolgit efficacy and tolerance in 76 patients with primary osteoarthritis in 8 rheumatological centers showed this preparation to reduce local pain syndrome in 70.1%, palpation pain sensitivity in 79.2%, joint swelling in 75.5% of patients. Unwanted reactions in the form of skin itch at the site of application were reported in 7.8% of cases.

Publication types

Clinical Trial
Comparative Study
English Abstract
Multicenter Study

MeSH terms

Administration, Topical
Adult
Aged
Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
Chronic Disease
Drug Therapy, Combination
Drug Tolerance
Female
Humans
Ibuprofen / administration & dosage*
Ibuprofen / adverse effects
Male
Middle Aged
Ointments
Osteoarthritis / drug therapy*

Substances

Anti-Inflammatory Agents, Non-Steroidal
Ointments
Ibuprofen