Antisense snoRNAs: a family of nucleolar RNAs with long complementarities to rRNA

Trends Biochem Sci. 1995 Jul;20(7):261-4. doi: 10.1016/s0968-0004(00)89039-8.

Abstract

A growing subset of small nucleolar RNAs (snoRNAs) contains long stretches of sequence complementarity to conserved sequences in mature ribosomal RNA (rRNA). This article reviews current knowledge about these complementarities and proposes that these antisense snoRNAs might function in pre-rRNA folding, base modification and ribosomal ribonucleoprotein assembly, in some cases acting as RNA chaperones.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Base Sequence
  • Cell Nucleolus / chemistry*
  • Conserved Sequence / genetics
  • Molecular Sequence Data
  • Nucleic Acid Conformation
  • Phylogeny
  • RNA, Antisense / chemistry*
  • RNA, Antisense / genetics
  • RNA, Ribosomal / chemistry*
  • RNA, Ribosomal / genetics
  • RNA, Ribosomal / metabolism
  • RNA, Small Nuclear / chemistry*
  • RNA, Small Nuclear / genetics
  • RNA, Small Nuclear / metabolism
  • Yeasts / genetics

Substances

  • RNA, Antisense
  • RNA, Ribosomal
  • RNA, Small Nuclear

Associated data

  • GENBANK/U26011
  • GENBANK/U26012
  • GENBANK/U26013
  • GENBANK/U26014
  • GENBANK/U26015
  • GENBANK/U26016