Low-dose chemonucleolysis combined with percutaneous nucleotomy in herniated cervical disks

J Spinal Disord. 1995 Jun;8(3):228-32. doi: 10.1097/00002517-199506000-00009.


The combination of low-dose chemonucleolysis with 500 IU chymopapain followed by an automated percutaneous nucleotomy of the cervical spine is a new procedure. A follow-up of at least 1 year of the first 22 patients showed in 19 patients good or excellent results. In one patient a fair result was obtained, and in two patients the symptoms were unchanged; one of these patients subsequently underwent diskectomy and anterior cervical spine fusion. Preoperatively, all patients showed a clear cervical disk herniation with predominantly radicular pain. The procedure has been performed so far in approximately 100 patients. No intra- or postoperative complications have been noted.

MeSH terms

  • Adult
  • Diskectomy, Percutaneous*
  • Female
  • Follow-Up Studies
  • Humans
  • Intervertebral Disc Chemolysis*
  • Intervertebral Disc Displacement / therapy*
  • Lumbosacral Region / surgery*
  • Male
  • Middle Aged
  • Neck / abnormalities
  • Pain
  • Treatment Outcome