Fifteen eyes with an initial myopia between -5.00 diopters (D) and -12.00 D were treated with radial keratotomy (RK) followed by photorefractive keratectomy (PRK) at least 6 months later and observed for 6 months to 24 months. Five eyes that had penetrating keratoplasty (PKP) were treated for residual ametropia by PRK and followed for up to two years. For the RK-treated eyes, mean pre-PRK refraction was -4.00 D sphere and + 1.25 D cylinder, which improved to -0.52 D sphere and + 0.73 D cylinder. Incidence of complications, including corneal haze, was extremely low in both the RK and PKP groups. In summary, PRK is a valuable method for correcting ametropia following RK and PKP, with risks similar to that for eyes having PRK as the initial refractive procedure.