Acute low-intensity microwave exposure increases DNA single-strand breaks in rat brain cells

Bioelectromagnetics. 1995;16(3):207-10. doi: 10.1002/bem.2250160309.


Levels of DNA single-strand break were assayed in brain cells from rats acutely exposed to low-intensity 2450 MHz microwaves using an alkaline microgel electrophoresis method. Immediately after 2 h of exposure to pulsed (2 microseconds width, 500 pulses/s) microwaves, no significant effect was observed, whereas a dose rate-dependent [0.6 and 1.2 W/kg whole body specific absorption rate (SAR)] increase in DNA single-strand breaks was found in brain cells of rats at 4 h postexposure. Furthermore, in rats exposed for 2 h to continuous-wave 2450 MHz microwaves (SAR 1.2 W/kg), increases in brain cell DNA single-strand breaks were observed immediately as well as at 4 h postexposure.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Analysis of Variance
  • Animals
  • Brain / radiation effects
  • DNA / radiation effects*
  • DNA Damage*
  • Electrophoresis
  • Hippocampus / radiation effects
  • Male
  • Microwaves*
  • Neurons / physiology
  • Neurons / radiation effects*
  • Rats
  • Rats, Sprague-Dawley


  • DNA