P3-like potential in rats

Electroencephalogr Clin Neurophysiol. 1993 Mar-Apr;88(2):151-4. doi: 10.1016/0168-5597(93)90066-x.


Auditory event-related potentials (ERPs) were recorded from the skull surface in unrestrained, unanesthetized rats. Infrequent deviant tones presented randomly within a sequence of repetitive tones enhanced a long-latency positive component peaking at 240 msec. This rodent ERP was comparable to the human P3a component in latency and sensitivity to stimulus probability. The rodent may provide a useful model for investigation of the neural sources of the P3.

MeSH terms

  • Acoustic Stimulation
  • Animals
  • Disease Models, Animal
  • Electroencephalography
  • Evoked Potentials, Auditory / physiology*
  • Frontal Lobe / physiology
  • Male
  • Probability
  • Rats
  • Rats, Inbred F344
  • Reaction Time
  • Signal Processing, Computer-Assisted
  • Visual Cortex / physiology