Beneficial effects of dextro-amphetamine in the treatment of vasodepressor syncope

Pacing Clin Electrophysiol. 1993 Jun;16(6):1235-9. doi: 10.1111/j.1540-8159.1993.tb01708.x.


Three patients with history of documented hypotension, near syncope, or syncope before or after the administration of isoproterenol during head-up tilt table are reported. Severe bradycardia was also noted in one patient. All three patients responded to the administration of 2.5 mg of oral dextroamphetamine 45 minutes prior to a repeat head-up tilt table study. The potent central and peripheral adrenergic agonist pharmacological properties of this drug permitted the prevention of severe vasodepressor syncope in these patients.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Bradycardia / complications
  • Bradycardia / drug therapy*
  • Dextroamphetamine / therapeutic use*
  • Female
  • Humans
  • Hypotension, Orthostatic / complications
  • Hypotension, Orthostatic / drug therapy*
  • Male
  • Middle Aged
  • Posture / physiology
  • Syncope / drug therapy*
  • Syncope / etiology


  • Dextroamphetamine