Expression of adhesion molecules by endothelial cells of early human decidua

Virchows Arch A Pathol Anat Histopathol. 1993;423(4):287-90. doi: 10.1007/BF01606892.

Abstract

The expression of adhesion molecules by endothelial cells (EC) of early human decidua was studied with monoclonal antibodies and the immunoperoxidase technique. Although E-selectin, INCAM-110 and VCAM-1 were poorly detected on decidual EC, ICAM-1, P-selectin and DR antigens were highly expressed by these cells, some of which showed high endothelial venule-like morphology. Our results suggest that decidual EC are activated, and are probably involved in the active recruitment of leucocytes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Adhesion Molecules / analysis*
  • Decidua / blood supply
  • Decidua / chemistry*
  • Endothelium, Vascular / chemistry*
  • Endothelium, Vascular / cytology
  • Female
  • HLA-DR Antigens / analysis*
  • Humans
  • Intercellular Adhesion Molecule-1
  • P-Selectin
  • Platelet Membrane Glycoproteins / analysis*
  • Pregnancy

Substances

  • Cell Adhesion Molecules
  • HLA-DR Antigens
  • P-Selectin
  • Platelet Membrane Glycoproteins
  • Intercellular Adhesion Molecule-1