Administration of medications via the intramuscular route: an integrative review of the literature and research-based protocol for the procedure

Appl Nurs Res. 1995 Feb;8(1):23-33. doi: 10.1016/s0897-1897(95)80279-7.


Administering injections is an activity inherent to nursing practice. A critical review of nursing fundamentals texts found that the "proper" procedure was often non-research based and reflected myths, traditions, and out-of-date recommendations regarding the technique. This article is an integrative review of the extensive research conducted by a variety of researchers in health-related disciplines during the last seven decades. The pertinent research is reviewed and critiqued and serves as the basis for a clinical practice protocol. This research-based procedure ensures efficient and effective nursing care related to intramuscular injections.

Publication types

  • Review

MeSH terms

  • Adult
  • Child
  • Clinical Nursing Research
  • Humans
  • Injections, Intramuscular / instrumentation
  • Injections, Intramuscular / methods
  • Injections, Intramuscular / nursing
  • Needles
  • Pharmaceutical Preparations / administration & dosage*
  • Syringes


  • Pharmaceutical Preparations