Liposomal amphotericin B for postoperative Aspergillus fumigatus endocarditis

Ann Thorac Surg. 1995 Apr;59(4):1015-7. doi: 10.1016/0003-4975(94)00743-q.

Abstract

A 10-month-old infant girl presented with Aspergillus fumigatus endocarditis localized to a Gore-Tex patch used as part of the repair for double-outlet right ventricle. A new liposomal preparation of amphotericin B combined with surgical vegectomy resulted in a successful outcome with no evidence of disease recurrence at 15 months' follow-up. Echocardiography provided an optimal modality for ongoing evaluation of therapeutic outcome.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B / therapeutic use*
  • Aspergillosis / drug therapy*
  • Aspergillosis / microbiology
  • Aspergillosis / surgery
  • Aspergillus fumigatus* / isolation & purification
  • Combined Modality Therapy
  • Debridement
  • Double Outlet Right Ventricle / surgery*
  • Endocarditis / drug therapy*
  • Endocarditis / microbiology
  • Endocarditis / surgery
  • Female
  • Humans
  • Infant
  • Liposomes
  • Postoperative Complications / drug therapy*
  • Postoperative Complications / surgery

Substances

  • Liposomes
  • Amphotericin B