Pallidotomy for Parkinson's disease

Neurosurg Clin N Am. 1995 Jan;6(1):105-12.


Ventroposterolateral pallidotomy was used in the surgical treatment of 259 patients suffering from intractable Parkinson's disease. Pallidotomy was equally effective against tremor, rigor, bradykinesia, and the L-dopa-induced dyskinesias. The effect of surgery seemed to be long-lasting, and side effects were rare. The author believes that the beneficial effect of pallidotomy is based on interruption of striopallidal and pallidosubthalamic pathways.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Globus Pallidus / surgery*
  • Humans
  • Male
  • Middle Aged
  • Parkinson Disease / surgery*
  • Postoperative Complications
  • Scotoma / etiology
  • Thalamus / surgery
  • Treatment Outcome