Selective methylation: an incorrect hypothesis

J Bacteriol. 1976 May;126(2):1009-11. doi: 10.1128/jb.126.2.1009-1011.1976.

Abstract

"Selective methylation," a hypothesis proposed to explain the discrepancy found in the degree of methyl deficiency of transfer ribonucleic acid, cannot be explained on the basis of some biological phenomenon.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Cell-Free System
  • Escherichia coli / analysis
  • Escherichia coli / enzymology
  • Escherichia coli / metabolism*
  • Guanine / analogs & derivatives
  • Guanine / analysis
  • Methionine / metabolism
  • Methylation
  • Mutation
  • N-Glycosyl Hydrolases / metabolism
  • RNA, Bacterial / analysis
  • RNA, Bacterial / metabolism*
  • RNA, Transfer / analysis
  • RNA, Transfer / metabolism*
  • S-Adenosylhomocysteine / analysis
  • Uracil / analogs & derivatives
  • Uracil / analysis
  • tRNA Methyltransferases / metabolism

Substances

  • RNA, Bacterial
  • Uracil
  • Guanine
  • RNA, Transfer
  • S-Adenosylhomocysteine
  • Methionine
  • tRNA Methyltransferases
  • N-Glycosyl Hydrolases