Digital clubbing. Demonstration with positron emission tomography

Chest. 1995 Apr;107(4):1172-3. doi: 10.1378/chest.107.4.1172.


Digital clubbing is a classic cutaneous manifestation of pulmonary disease, but its mechanism is unknown. We describe a patient with lung cancer and clubbing in whom positron emission tomography (PET) demonstrated, for the first time, that increased glucose metabolism occurs at the nailbed. PET may contribute to future investigations of digital clubbing.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Squamous Cell / complications
  • Carcinoma, Squamous Cell / metabolism
  • Female
  • Glucose / metabolism*
  • Humans
  • Lung Neoplasms / complications
  • Lung Neoplasms / metabolism
  • Middle Aged
  • Osteoarthropathy, Secondary Hypertrophic / diagnostic imaging*
  • Osteoarthropathy, Secondary Hypertrophic / etiology
  • Osteoarthropathy, Secondary Hypertrophic / metabolism*
  • Tomography, Emission-Computed*


  • Glucose