Human papillomavirus infection is transient in young women: a population-based cohort study

J Infect Dis. 1995 Apr;171(4):1026-30. doi: 10.1093/infdis/171.4.1026.


The prevalence of human papillomavirus (HPV) infection in cervical cell scrapes from a cohort of 276 young women was determined by a general two-step polymerase chain reaction. HPV infection fluctuated among young women during a 2-year interval. The total prevalence of HPV infection decreased from 21% to 8.3%. The most prevalent HPV types at enrollment were HPV-16 (3.3%) and HPV-6 (2.9%). At follow-up, the most common type was HPV-16 (2.9%), while no HPV-6 was detected. In 2 women only, the same HPV type persisted. Regression of HPV infection was found in 80% of the women. A new HPV type-specific infection was detected in 7.2% of the women and was independently associated with a new sex partner or an abnormal smear since enrollment.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cervix Uteri / virology
  • Cohort Studies
  • DNA, Viral / analysis
  • Female
  • Humans
  • Papillomaviridae / genetics
  • Papillomaviridae / isolation & purification*
  • Papillomavirus Infections / epidemiology*
  • Papillomavirus Infections / virology
  • Polymerase Chain Reaction / methods
  • Prevalence
  • Sweden / epidemiology
  • Tumor Virus Infections / epidemiology*
  • Tumor Virus Infections / virology
  • Uterine Cervical Diseases / epidemiology*
  • Uterine Cervical Diseases / virology


  • DNA, Viral