Invasive pulmonary aspergillosis complicating allergic bronchopulmonary aspergillosis

Respir Med. 1995 Feb;89(2):143-5. doi: 10.1016/0954-6111(95)90198-1.


Invasive pulmonary aspergillosis is a frequent complication in immunocompromised patients. The role of the prolonged use of steroids in predisposing to invasive aspergillosis has been recognized, but exceptionally described in asthmatic patients. We report the case of a 59-year-old woman with bronchial asthma treated with steroid therapy for a long time, who developed an invasive pulmonary aspergillosis with an unusual combination of invasive and allergic disease. It seems reasonable to think that allergic disease due to allergic bronchopulmonary aspergillosis (ABPA) preceded the terminal invasive process. Adjunctive therapy with antifungal agents in patients with ABPA is considered, since there is the risk of an invasive pulmonary aspergillosis.

Publication types

  • Case Reports

MeSH terms

  • Aspergillosis / complications*
  • Aspergillosis / diagnostic imaging
  • Aspergillosis, Allergic Bronchopulmonary / complications
  • Aspergillosis, Allergic Bronchopulmonary / diagnostic imaging
  • Aspergillus fumigatus*
  • Asthma / complications*
  • Asthma / diagnostic imaging
  • Asthma / drug therapy
  • Fatal Outcome
  • Female
  • Humans
  • Lung Diseases, Fungal / complications*
  • Lung Diseases, Fungal / diagnostic imaging
  • Middle Aged
  • Prednisolone / therapeutic use
  • Radiography


  • Prednisolone