Treatment of ocular fungal infections with oral fluconazole

Am J Ophthalmol. 1995 Apr;119(4):477-81. doi: 10.1016/s0002-9394(14)71234-6.


Purpose: We treated five patients who had ocular fungal infections with oral fluconazole to determine its safety and effectiveness.

Methods: We reviewed the case histories of the five patients. One patient had coccidioidomycosis and four had endogenous Candida endophthalmitis.

Results: The intraocular fungal infection resolved in all patients.

Conclusion: Fluconazole appears to be a safe and effective antifungal agent that can be administered orally and may be a useful agent for treating some intraocular fungal infections.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Adult
  • Aged
  • Candidiasis / drug therapy*
  • Coccidioidomycosis / drug therapy*
  • Drug Tolerance
  • Endophthalmitis / drug therapy*
  • Endophthalmitis / microbiology
  • Eye Infections, Fungal / drug therapy*
  • Female
  • Fluconazole / administration & dosage
  • Fluconazole / adverse effects
  • Fluconazole / therapeutic use*
  • Humans
  • Male
  • Middle Aged


  • Fluconazole