Malignancy in Maffucci's syndrome

Dermatol Clin. 1995 Jan;13(1):73-8.

Abstract

Maffucci's syndrome is characterized by multiple enchondromas and subcutaneous hemangiomas. These tumors typically present in early childhood and may lead to significant skeletal deformities. Malignant transformations are a common feature of this syndrome and have been reported in approximately 30% of reported cases, with chondrosarcomas being the most common.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Bone Neoplasms / pathology
  • Child
  • Chondrosarcoma / pathology
  • Enchondromatosis / diagnosis
  • Enchondromatosis / genetics*
  • Enchondromatosis / pathology
  • Follow-Up Studies
  • Hemangioma / pathology
  • Humans
  • Middle Aged
  • Precancerous Conditions / pathology*
  • Soft Tissue Neoplasms / pathology