Adverse Health Effects of Lead at Low Exposure Levels: Trends in the Management of Childhood Lead Poisoning

Toxicology. 1995 Mar 31;97(1-3):11-7. doi: 10.1016/0300-483x(94)02963-u.


An extensive database has provided a direct link between low-level lead exposure during early development and deficits in neurobehavioral-cognitive performance evident late in childhood through adolescence. These consistent studies have demonstrated the presence of a constellation of neurotoxic and other adverse effects of lead at blood lead (BPb) levels at least as low as 10 micrograms/dl). Federal agencies and advisory groups have redefined childhood lead poisoning as a BPb level of 10 micrograms/dl. Before discussing some of these studies in greater detail, the pervasiveness of this entirely preventable disease today in millions of American children must be recognized.

Publication types

  • Review

MeSH terms

  • Child
  • Child Behavior Disorders / chemically induced
  • Cognition Disorders / chemically induced
  • Environmental Exposure
  • Humans
  • Lead / adverse effects*
  • Lead / blood
  • Lead Poisoning / therapy*


  • Lead