Cloning of a canine cDNA homologous to the human transforming growth factor-beta 1-encoding gene

Gene. 1995 Apr 3;155(2):307-8. doi: 10.1016/0378-1119(94)00903-6.

Abstract

A 1369-bp cDNA that encodes a homolog of the human transforming growth factor-beta 1 (TGF-beta 1) has been isolated from canine endothelial cells using a combination of PCR and traditional plaque-screening methods. The deduced 390-amino-acid sequence of the canine TGF-beta 1 precursor has 91-94% identity to those deduced from the previously described human and mouse TGF-beta 1 clones.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cloning, Molecular
  • DNA, Complementary / genetics
  • Dogs
  • Humans
  • Molecular Sequence Data
  • Sequence Homology
  • Transforming Growth Factor beta / genetics*

Substances

  • DNA, Complementary
  • Transforming Growth Factor beta

Associated data

  • GENBANK/L34956