Rapid antibody test for fragile X syndrome

Lancet. 1995 May 6;345(8958):1147-8. doi: 10.1016/s0140-6736(95)90979-6.


Fragile X syndrome is the most common known cause of inherited mental retardation. Identification of patients and carriers of fragile X syndrome is usually done with a DNA test system but we have developed a rapid antibody to identify fragile X patients. This non-invasive test requires only 1 or 2 drops of blood and can be used for screening large groups of mentally retarded people and neonates for fragile X syndrome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Monoclonal
  • DNA / genetics
  • Female
  • Fragile X Mental Retardation Protein
  • Fragile X Syndrome / blood
  • Fragile X Syndrome / diagnosis*
  • Fragile X Syndrome / genetics
  • Genetic Carrier Screening
  • Heterozygote
  • Humans
  • Male
  • Nerve Tissue Proteins / blood
  • RNA-Binding Proteins / blood


  • Antibodies, Monoclonal
  • FMR1 protein, human
  • Nerve Tissue Proteins
  • RNA-Binding Proteins
  • Fragile X Mental Retardation Protein
  • DNA