Severe ciguatera poisoning in Madagascar: a case report

Toxicon. 1994 Dec;32(12):1539-42. doi: 10.1016/0041-0101(94)90312-3.


In a single outbreak on the East coast of Madagascar, more than 500 people, 98 of whom died, were poisoned by the flesh of a shark, Carcharhinus amboinensis. From clinical symptoms it can be concluded that this poisoning is due to ciguatera toxins. It is the first case of a severe outbreak caused by a shark, and it is the first case with a mortality rate of 20%.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Ciguatera Poisoning*
  • Coma / chemically induced
  • Foodborne Diseases / mortality*
  • Humans
  • Madagascar
  • Sharks / metabolism*