Phenotypic definitions of psychotic illness for molecular genetic research

Am J Med Genet. 1994 Dec 15;54(4):365-71. doi: 10.1002/ajmg.1320540416.


New approaches to establish the molecular genetic bases of psychotic illness have recently been suggested which make different demands on diagnosticians attempting to provide reliable and valid phenotypic definitions. The diagnostic problems that have arisen to date and some solutions to these are considered. In addition, future diagnostic requirements for linkage and association studies are discussed.

Publication types

  • Review

MeSH terms

  • Cognition
  • Genetics, Medical
  • Humans
  • Molecular Biology
  • Phenotype
  • Psychotic Disorders / classification
  • Psychotic Disorders / diagnosis
  • Psychotic Disorders / genetics*
  • Research Design*
  • Schizophrenia / genetics