Relapse of tularemia after aminoglycoside therapy: case report and discussion of therapeutic options

Clin Infect Dis. 1995 Jan;20(1):174-5. doi: 10.1093/clinids/20.1.174.


We describe a patient with ulceroglandular tularemia who initially responded to therapy with gentamicin but then clinically relapsed. Ciprofloxacin was subsequently given for 28 days, and the patient was clinically cured. Aminoglycosides have been considered the drugs of choice in the treatment of tularemia; however, potential alternative treatments do exist. We review the English-language literature on this topic.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Ciprofloxacin / therapeutic use*
  • Female
  • Gentamicins / therapeutic use
  • Humans
  • Recurrence
  • Tularemia / drug therapy*


  • Anti-Bacterial Agents
  • Gentamicins
  • Ciprofloxacin