Regrowth of grafted human scalp hair after removal of the bulb

Dermatol Surg. 1995 Apr;21(4):312-3. doi: 10.1111/j.1524-4725.1995.tb00179.x.


Background: The bulbar region of the hair follicle contains the dermal papilla, hair germinative epithelial component, and active melanocytes. Thus, it has been assumed that the bulbar region plays a central role in hair growth, differentiation, and pigmentation.

Objective: To assess the regenerative capacity of human hair.

Methods: Individual anagen hair follicles were isolated from the occipital scalp and grafted onto the leg after removal of the bulb.

Results: The grafts of follicles from which the bulb and complete papilla have been excised regenerated new papillae and grew new pigmented hairs.

Conclusion: The middle portion of the outer root sheath and dermal sheath may also contain epithelial, mesenchymal, and melanocyte reservoirs.

MeSH terms

  • Hair / growth & development*
  • Hair / transplantation*
  • Humans
  • Methods
  • Scalp
  • Transplantation, Autologous