Usefulness of pulsed-field gel electrophoresis in the epidemiological analysis of Staphylococcus aureus isolates with decreased susceptibility to teicoplanin

Eur J Clin Microbiol Infect Dis. 1995:14 Suppl 1:S3-5.

Abstract

Pulsed-field gel electrophoresis for analysis of comparatively mega-base sized chromosomal restriction fragments is an important molecular technique in the epidemiological study of a variety of nosocomial pathogens. The usefulness of this approach is demonstrated in the evaluation of Staphylococcus aureus isolates exhibiting decreased susceptibility to teicoplanin in two clinical settings: multiple cultures from a single patient and isolates from different patients within the same hospital.

MeSH terms

  • Cross Infection / drug therapy
  • Cross Infection / microbiology*
  • DNA, Bacterial / analysis*
  • Drug Resistance, Microbial
  • Electrophoresis, Gel, Pulsed-Field*
  • Humans
  • Microbial Sensitivity Tests
  • Molecular Epidemiology
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / microbiology*
  • Staphylococcus aureus / drug effects
  • Staphylococcus aureus / genetics*
  • Teicoplanin / pharmacology

Substances

  • DNA, Bacterial
  • Teicoplanin