What are the real problems for patients with functional dyspepsia?

Scand J Gastroenterol. 1995 Feb;30(2):97-100. doi: 10.3109/00365529509093244.


Background: Patients with functional dyspepsia (FD) have more complaints than just the dyspepsia.

Method: One hundred FD patients were assessed with regard to psychologic, medical, and social factors, before randomization, in a study of cognitive therapy. They were asked to list their main problem areas or 'target complaints'.

Results: Dyspepsia was the third most frequent target complaint (26 patients), and anxiety was the most frequent one (65 patients). Patients identifying dyspepsia as a target complaint differed from the other FD patients in several aspects. They had significantly more dyspeptic symptoms (p < 0.05) and scored significantly higher on multiple somatic complaints (p = 0.001), depression (p = 0.025), general psychopathology (p = 0.043), the global assessment scale (p = 0.001), and the General Health Questionnaire (p = 0.040). However, they did not have more somatic predisposing factors like consumption of alcohol and coffee or infection with Helicobacter pylori than the patients with other target complaints.

Conclusions: Anxiety and not dyspepsia was the most frequent target complaint, and patients who identified dyspepsia as a target complaint did not have more somatic predisposing factors.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anxiety / epidemiology*
  • Causality
  • Cognitive Behavioral Therapy
  • Depression / epidemiology
  • Dyspepsia / epidemiology
  • Dyspepsia / psychology*
  • Dyspepsia / therapy
  • Female
  • Helicobacter Infections / epidemiology
  • Helicobacter pylori
  • Humans
  • Interview, Psychological
  • Life Style
  • Male
  • Psychiatric Status Rating Scales
  • Risk Factors
  • Somatoform Disorders / epidemiology