Embryonic development of the larval body wall musculature of Drosophila melanogaster

Trends Genet. 1995 Apr;11(4):153-9. doi: 10.1016/s0168-9525(00)89030-7.


The somatic, or body wall, muscles of the larva of Drosophila melanogaster are composed of an elaborate pattern of segmentally repeating fibers that form during embryogenesis. The primordia of these muscles progress from morphologically indistinct mesodermal cells to multinucleate syncytia with unique characteristics that include shape, size, location and attachment to the epidermis. Although relatively little is known about the development of the musculature and the mechanisms by which this elaborate pattern is achieved, recent progress has begun to reveal key players in this process.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Cell Differentiation
  • Drosophila melanogaster / embryology*
  • Larva
  • Muscles / cytology
  • Muscles / embryology*
  • Species Specificity
  • Vertebrates / genetics