Macroemboli and microemboli during cardiopulmonary bypass

Ann Thorac Surg. 1995 May;59(5):1300-3. doi: 10.1016/0003-4975(95)00105-t.


Macroscopic and microscopic emboli of gas, biologic aggregates, and inorganic debris can occur during cardiac operations with cardiopulmonary bypass and may result in end-organ ischemia. In the current era pump-generated embolism is a diminishing cause of perioperative neurologic injury, which now appears to be related mostly to atheroembolism from manipulation of the atherosclerotic ascending aorta, and presents a continuing technical challenge to the surgeon.

Publication types

  • Review

MeSH terms

  • Cardiac Surgical Procedures / adverse effects*
  • Cardiopulmonary Bypass / adverse effects*
  • Humans
  • Intracranial Embolism and Thrombosis / diagnosis
  • Intracranial Embolism and Thrombosis / etiology*
  • Intracranial Embolism and Thrombosis / prevention & control