Outcome of extremely low-birth-weight infants: 1980-1990

Acta Paediatr. 1994 Dec;83(12):1244-8. doi: 10.1111/j.1651-2227.1994.tb13005.x.


Neonatal and follow-up data of infants from the special care nursery whose birth weights were < 750 g, born between 1980 and 1990, were reviewed. There was a 20% relative improvement in the odds of surviving the neonatal period, a 16% improvement in the odds of being discharged and a 19% improvement in the odds of surviving until 2 years of age with each consecutive year. Home oxygen use increased significantly over the study period. The neurodevelopmental outcomes of infants were similar over the 11-year period, with 53% being classified as neurologically normal, with a mean developmental index of 83 at 1 to 2 years of age. We conclude that there has been an improved survival of infants with birth weights < 750 g in our institution, and that the overall incidence of serious neurodevelopmental deficits among survivors has remained stable.

MeSH terms

  • Birth Weight
  • Brain Damage, Chronic / etiology
  • Brain Damage, Chronic / mortality*
  • Cause of Death
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Infant, Low Birth Weight*
  • Infant, Newborn
  • Infant, Premature, Diseases / etiology
  • Infant, Premature, Diseases / mortality*
  • Infant, Small for Gestational Age
  • Length of Stay / statistics & numerical data
  • Male
  • Neurologic Examination
  • Rhode Island / epidemiology
  • Risk Factors
  • Survival Rate