Solid alveolar rhabdomyosarcoma with a t(2;13)

Cancer Genet Cytogenet. 1995 Apr;80(2):107-9. doi: 10.1016/0165-4608(94)00170-g.


We report a child with a progressive "solid alveolar rhabdomyosarcoma" in whom analysis of tumor cells revealed a t(2;13) translocation characteristic of the classical alveolar subtype. Both subtypes of alveolar rhabdomyosarcoma are associated with a poor response to treatment and the occurrence of this translocation in both is suggestive of a common biologic origin.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Child, Preschool
  • Chromosomes, Human, Pair 13*
  • Chromosomes, Human, Pair 2*
  • Combined Modality Therapy
  • Humans
  • Rhabdomyosarcoma, Alveolar / drug therapy
  • Rhabdomyosarcoma, Alveolar / genetics*
  • Rhabdomyosarcoma, Alveolar / radiotherapy
  • Translocation, Genetic*