Identification of pioneer viridans streptococci in the oral cavity of human neonates

J Med Microbiol. 1995 Jan;42(1):67-72. doi: 10.1099/00222615-42-1-67.


Three hundred and sixty-seven strains of pioneer streptococci isolated from the mouths of 40 healthy, full-term infants during the first month of life were examined by two taxonomic schemes that incorporated biochemical and physiological characteristics, IgA1 protease production and glycosidase activities. Streptococcus mitis biovar 1 and S. oralis comprised 55.0% of the pioneer streptococci isolated from neonates. S. salivarius constituted 25.3% of the isolates, while S. anginosus, S. mitis biovar 2, S. sanguis and S. gordonii accounted collectively for 11.4%. Difficulties in identifying streptococci were encountered and 8.4% of the 367 isolates could not be assigned to a recognised species.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bacterial Proteins / analysis
  • Bacterial Typing Techniques
  • Cluster Analysis
  • Humans
  • Infant, Newborn
  • Longitudinal Studies
  • Mouth / microbiology*
  • Streptococcus / classification
  • Streptococcus / isolation & purification*
  • Streptococcus sanguis / classification
  • Streptococcus sanguis / isolation & purification


  • Bacterial Proteins