Although the mandatory mesenterico-portal resection in patients with cancer of the pancreas is thought to have no anticancer effect, this wide exeresis does not increase operative mortality significantly. We performed this operation for a large benign tumour englobing the portal vein. The tumour was completely removed with no major per-operative problem with haemostasis. Venous circulation was reestablished by direct suture without prosthesis. The post-operative period was uneventful and the patient was asymptomatic three years later. We emphasize the technical procedure and draw attention to this operation in non-cancer cases.