Five patients treated with radiotherapy and surgery for oral malignant tumors had a total of 20 Brånemark implants placed in irradiated bone of the mandible. The radiotherapy dose varied between 25 and 64 Gy (mean 40.3 Gy) with a biologically effective dose varying between 33.4 and 106.9. One implant did not osseointegrate, but 19 remain stable after 3 to 6 years of observation. The oral surgery procedures were carried out without adjunct hyperbaric oxygen therapy, and the successful results support the view that such adjunctive measures are not always necessary in the oral rehabilitation after radiotherapy.