Relationship of rheumatoid factor to lung diffusion capacity in smoking and non-smoking patients with rheumatoid arthritis

Scand J Rheumatol. 1995;24(2):119-20. doi: 10.3109/03009749509099296.


We studied the relationship of serum rheumatoid factor (RF) and certain other variables to lung diffusion capacity for carbon monoxide (DLCO) in patients with rheumatoid arthritis (RA). In non-smoking patients none of the examined variables correlated significantly to DLCO whereas in smokers RF showed a significant (p < 0.01) negative correlation in this respect. These results indicate that smoking in connection with RF may contribute to reduced DLCO in RA patients.

MeSH terms

  • Adult
  • Aged
  • Arthritis, Rheumatoid / blood
  • Arthritis, Rheumatoid / physiopathology*
  • Humans
  • Middle Aged
  • Pulmonary Diffusing Capacity*
  • Rheumatoid Factor / analysis*
  • Smoking*


  • Rheumatoid Factor