Parameters that predict success for natural cycle in vitro fertilization-embryo transfer

Fertil Steril. 1995 Jun;63(6):1251-4. doi: 10.1016/s0015-0282(16)57606-7.


Objectives: To analyze our natural cycle IVF-ET experience in order to identify parameters predictive for success.

Design: Retrospective study.

Setting: Private-based reproductive center.

Patients: All patients who presented for IVF-ET interested in unmedicated cycles.

Main outcome measures: Routine monitoring for IVF-ET was performed. In addition, serum values for FSH, PRL, E2, and P were analyzed.

Results: Day 3 FSH values were not useful, whereas elevated day 3 LH values adversely correlated with outcome. Age was the single most important predictor of success. With two cycles, 87.5% of pregnancies occurred.

Conclusion: With proper patient selection, natural cycle IVF-ET results can be substantially improved.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Factors
  • Chorionic Gonadotropin / administration & dosage
  • Chorionic Gonadotropin / therapeutic use
  • Embryo Transfer*
  • Estradiol / blood
  • Feedback
  • Female
  • Fertilization in Vitro*
  • Follicle Stimulating Hormone / blood
  • Humans
  • Luteinizing Hormone / blood
  • Pregnancy
  • Progesterone / blood
  • Prolactin / blood
  • Retrospective Studies
  • Time Factors


  • Chorionic Gonadotropin
  • Progesterone
  • Estradiol
  • Prolactin
  • Luteinizing Hormone
  • Follicle Stimulating Hormone