Selenium deficiency and decreased coenzyme Q levels

Mol Aspects Med. 1994:15 Suppl:s103-7. doi: 10.1016/0098-2997(94)90019-1.

Abstract

The effect of long-term (18 months) selenium deficiency on the levels of liver coenzyme Q was studied in the rat. Levels of coenzyme Q9 and coenzyme Q10 in the liver of selenium-deficient rats were 40 and 67% of the levels in selenium-adequate animals, respectively. The results are similar to the findings using a shorter feeding period.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Coenzymes
  • Glutathione Transferase / metabolism
  • Iodide Peroxidase / metabolism
  • Liver / metabolism*
  • Male
  • Rats
  • Rats, Wistar
  • Selenium / deficiency*
  • Selenium / physiology
  • Thyroid Hormones / blood
  • Ubiquinone / analogs & derivatives*
  • Ubiquinone / metabolism*

Substances

  • Coenzymes
  • Thyroid Hormones
  • Ubiquinone
  • Iodide Peroxidase
  • Glutathione Transferase
  • coenzyme Q10
  • Selenium
  • ubiquinone 9