Photovoltage of rods and cones in the macaque retina

Science. 1995 May 19;268(5213):1053-6. doi: 10.1126/science.7754386.


The kinetics, gain, and reliability of light responses of rod and cone photoreceptors are important determinants of overall visual sensitivity. In voltage recordings from photoreceptors in an intact primate retina, rods were found to be functionally isolated from each other, unlike the tightly coupled rods of cold-blooded vertebrates. Cones were observed to receive excitatory input from rods, which indicates that the cone pathway also processes rod signals. This input might be expected to degrade the spatial resolution of mesopic vision.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • In Vitro Techniques
  • Kinetics
  • Light*
  • Macaca fascicularis
  • Membrane Potentials / radiation effects
  • Photic Stimulation / methods
  • Retinal Cone Photoreceptor Cells / physiology*
  • Retinal Cone Photoreceptor Cells / radiation effects
  • Retinal Rod Photoreceptor Cells / physiology*
  • Retinal Rod Photoreceptor Cells / radiation effects