Organization of organelles and membrane traffic by microtubules

Curr Opin Cell Biol. 1995 Feb;7(1):55-64. doi: 10.1016/0955-0674(95)80045-x.


Organelles of the central membrane system of higher eukaryotes have been shown to utilize microtubules both for maintenance of their characteristic spatial distributions and for efficient transport of their protein and lipid to diverse sites within the cell. Recent work addressing the mechanisms that underlie this organization provides new insights regarding the roles of microtubules and microtubule motors in influencing organelle dynamics and specific membrane traffic routes through the cytoplasm.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Transport / physiology
  • Endosomes / metabolism
  • Endosomes / ultrastructure
  • Eukaryotic Cells
  • Intracellular Membranes / metabolism*
  • Intracellular Membranes / ultrastructure
  • Microtubules / metabolism*
  • Microtubules / ultrastructure
  • Organelles / ultrastructure*
  • Phosphorylation