Microtubules and microtubule-associated proteins

Curr Opin Cell Biol. 1995 Feb;7(1):72-81. doi: 10.1016/0955-0674(95)80047-6.


Microtubule research is becoming increasingly diverse, reflecting the many isoforms and modifications of tubulin and the many proteins with which microtubules interact. Recent advances are particularly visible in four areas: microtubule motor proteins (their structures, stepping modes, and forces); microtubule nucleation (the roles of centrosomes and gamma-tubulin); tubulin folding (mediated by cytoplasmic chaperones); and the expanding list of microtubule-associated proteins, knowledge of their phosphorylation states, and information on their effects on microtubule dynamics.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Movement / physiology
  • Centrosome / chemistry
  • Microtubule-Associated Proteins / chemistry*
  • Microtubules / ultrastructure*
  • Molecular Chaperones / chemistry
  • Sequence Homology, Nucleic Acid
  • Tubulin / chemistry
  • Tubulin / metabolism
  • tau Proteins / physiology


  • Microtubule-Associated Proteins
  • Molecular Chaperones
  • Tubulin
  • tau Proteins